Anticonvulsant medication can treat Epilepsy effectively

Nowadays, a lot of people suffering from epilepsy are looking for reliable and effective treatments. Topamax is proved to be most effective anticonvulsant used for treating epilepsy. Topamax is also used with other medicines to control seizures. Topamax is considered as generic topiramate and is useful in treating severe seizures and mild seizures as well.

Topamax is used for children and adults and is approved by FDA. This medicine is also very helpful in relieving migraine headaches. Apart from this, it is useful in treating Lennux-Gastaut syndrome, obsessive compulsive and traumatic stress disorder.

Topamax is approved by FDA , the only anticonvulsant getting approval from FDA treats mild to severe seizures and also helps with autism problems.

Start Slowly

When you start taking Topamax dose, it is better to start with a low dose and gradually increase the dosage as prescribed by your doctor. Overdose of this medication can lead to problems and thus it should be taken in right dosage to keep problems away.

Some common  symptoms of this medication are agitation, bone pain, depression, increased hunger, fainting, stomach pain, convulsion, stress etc.,

You need care while you take Topamax

While taking this medication you need care. Take only the generic after discussing with the physician. Avoid the medication if you are suffering from liver or kidney disease, asthma, bronchitis, glaucoma and in case you had undergone any surgery, do not take this medication.

Pregnant women should speak to their doctor before you start with this medicine. Though the effects of this medicine aren’t tested or verified, still if you are pregnant, doctor’s suggestion is must.

You should take this medicine as per your doctor’s advice to avoid related side effects. You can take this medicine with food or without food.

Do not take double dose even if you miss one dose. If you forget first dose and don’t take it along with second dose. You can skip first dose to avoid overdose of this medicine.

Anticonvulsants are normally used to prevent the reoccurrence of seizures and also terminate electrical and clinical activity. Anticonvulsants are reserved for treating people having higher risk of recurrent seizures.

More than 60% of people suffering from epilepsy are treating using anticonvulsants. Many patients also get adverse effects using these drugs whereas others suffer from seizures that are stubborn to medical therapy. For individuals having more than one unprovoked seizure, anticonvulsant treatment is recommended.  Anticonvulsants are normally not recommended till the patient has chances for recurrence.

Anticonvulsant medication is backbone for seizure treatment. The choice of drug depends on accurate diagnosis on one’s epileptic syndrome because response to a particular anticonvulsant varies among different syndrome types.

Anticonvulsants have their own mechanism to treat various types of seizure. Neurologists treat different seizures with different anticonvulsants depending upon the diagnosis and its results. For people suffering with epilepsy, your neurologist can help you know which anticonvulsant will work better for you. Trust your neurologist and follow his/her instruction to avoid any problems and get rid of epilepsy safely.

Bipolar Disorder treatment through Anticonvulsant

Many anticonvulsant medications are considered as mood stabilizers and are used to prevent or treat mood occurrence in bipolar disorder. Initially anticonvulsants prescription was given to those who didn’t show response to lithium. Nowadays they are prescribed with lithium, antipsychotic drug or alone in order to control mania.

Anticonvulsants work towards calming hyperactivity caused in brain in many ways. That is the reason some of the anticonvulsants are used to prevent migraine, treat brain disorders and epilepsy. They are recommended to those having rapid cycling like 4 or more than 4 episodes of depression or mania a year.

Anticonvulsants that are used in treating bipolar disorder are

  • Lamictal
  • Tegretol
  • Depakote Depakene

These medicines are prescribed depending on the type of bipolar symptoms are helpful in treating. For example Tegretol and Depakote are effective in treating symptoms of depression and mania while Lamictal is helpful in preventing future episodes instead of treating current episodes. Tegretol and Depakote are effective in treating acute episodes rather than using them as preventative treatments.

Other anticonvulsants are not much effective when it comes to treating bipolar disorder mood symptoms whereas others like Lyrica, Topamax, and Neurontin are normally used “off label” for some other problems like weight loss and anxiety.

Each anticonvulsant works differently on our brain, so the experience with drug may differ depending on the drug you are taking. In short,  you can experience the maximum effective of these drugs only after using it for several weeks.

Side Effects of Anticonvulsant

Your doctor may ask you to take blood tests occasionally in order to keep track of your health while you are consuming anticonvulsant. Some anticonvulsants can lead to kidney or liver damage, lower the blood platelets. Your blood platelets help in blood clotting.

Each anticonvulsant may differ slightly in the side effects they show. Common side effects seen are

  • Rash
  • Weight gain
  • Drowsiness
  • Fatigue
  • Dizziness
  • Nausea
  • Tremor

Most of the above side effects mentioned above reduce over a period of time.  Side effects that last for long term vary from one drug to another.

Pregnant women should avoid taking anticonvulsants without discussing with their doctor as it might increase birth defect risks. Some anticonvulsants also lead to liver problems in the long run so the doctor can also monitor the liver on a regular basis.

Anticonvulsants interaction with other drugs is obvious and even with aspirin leading to serious problems. Make sure you tell your doctor if you are taking any herbs, drugs or supplements. Don’t consume any substance during your treatment without discussing with  the doctor.

There are risks associated with bipolar disorder during pregnancy and it can get worse during your pregnancy. Pregnant women having bipolar disorder are seven times at risk in comparison to pregnant women who aren’t suffering from bipolar disorder. If you are pregnant and suffering from bipolar disorder, discuss with your doctor about possible complication so that you doctor can guide you better and help you with related treatment.


Why is this medication prescribed?

Pregabalin is used to relieve neuropathic pain (pain from damaged nerves) that can occur in your arms, hands, fingers, legs, feet, or toes if you have diabetes or in the area of your rash if you have had shingles (a painful rash that occurs after infection with herpes zoster). It is also used to treat fibromyalgia (a long-lasting condition that may cause pain, muscle stiffness and tenderness, tiredness, and difficulty falling asleep or staying asleep). Pregabalin is used with other medications to treat certain types of seizures in people with epilepsy. Pregabalin is in a class of medications called anticonvulsants. It works by decreasing the number of pain signals that are sent out by damaged nerves in the body.

How should this medicine be used?

Pregabalin comes as a capsule to take by mouth. It is usually taken with or without food two or three times a day. Take pregabalin at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand.

Your doctor will probably start you on a low dose of pregabalin and may gradually increase your dose during the first week of treatment.

Take pregabalin exactly as directed. Pregabalin may be habit forming. Do not take a larger dose, take it more often, or take it for a longer period of time than prescribed by your doctor.

Pregabalin may help control your symptoms but will not cure your condition. It may take several weeks or longer before you feel the full benefit of pregabalin. Continue to take pregabalin even if you feel well. Do not stop taking pregabalin without talking to your doctor, even if you experience side effects such as unusual changes in behavior or mood. If you suddenly stop taking pregabalin, you may experience withdrawal symptoms, including trouble falling asleep or staying asleep, nausea, diarrhea, headaches, or seizures. Your doctor will probably decrease your dose gradually over at least one week.

Your doctor or pharmacist will give you the manufacturer’s patient information sheet (Medication Guide) when you begin treatment with pregabalin and each time you refill your prescription. Read the information carefully and ask your doctor or pharmacist if you have any questions. You can also visit the Food and Drug Administration (FDA) website ( or the manufacturer’s website to obtain the Medication Guide.

Other uses for this medicine

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

What special precautions should I follow?

Before taking pregabalin,

  • tell your doctor and pharmacist if you are allergic to pregabalin, any other medications, or any of the ingredients in pregabalin capsules. Ask your pharmacist for a list of the ingredients.
  • tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: angiotensin converting enzyme (ACE) inhibitors such as benazepril (Lotensin, in Lotrel), captopril (Capoten, in Capozide), enalapril (Vasotec, in Vaseretic, Lexxel), fosinopril (Monopril), lisinopril (Prinivil, Zestril, in Prinzide, Zestoretic), moexipril (Univasc, in Uniretic), perindopril (Aceon), quinapril (Accupril, in Accuretic, Quinaretic), ramipril (Altace), and trandolapril (Mavik, in Tarka); antidepressants; antihistamines; medications for anxiety, including lorazepam (Ativan); medications for mental illness or seizures; certain medications for diabetes such as pioglitazone (Actos, in Duetact) and rosiglitazone (Avandia, in Avandaryl, Avandamet); narcotic pain medications, including oxycodone (OxyContin, in Percocet, others); sedatives; sleeping pills; and tranquilizers. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
  • tell your doctor if you drink or have ever drunk large amounts of alcohol, use or have ever used street drugs, or have overused prescription medications. Also tell your doctor if you have or have ever had swelling of the eyes, face, lips, tongue, or throat; problems with your vision, bleeding problems or a low number of platelets (type of blood cell needed for blood clotting) in your blood, or heart or kidney disease.
  • tell your doctor if you are pregnant, or if you or your partner plans to become pregnant. Also tell your doctor if you are breast-feeding. If you or your partner becomes pregnant while you are taking pregabalin, call your doctor. Pregabalin has caused decreased fertility in male animals and birth defects in the offspring of male and female animals who were treated with the medication. There is not enough information to tell if pregabalin causes these problems in humans.
  • if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking pregabalin.
  • you should know that pregabalin may make you dizzy or drowsy. Do not drive a car operate machinery, or do other dangerous activities until you know how this medication affects you. Ask your doctor when you may do these activities.
  • do not drink alcohol while taking pregabalin. Alcohol can add to the drowsiness caused by this medication.
  • you should know that your mental health may change in unexpected ways and you may become suicidal (thinking about harming or killing yourself or planning or trying to do so) while you are taking pregabalin for the treatment of epilepsy, mental illness, or other conditions. A small number of adults and children 5 years of age and older (about 1 in 500 people) who took anticonvulsants such as pregabalin to treat various conditions during clinical studies became suicidal during their treatment. Some of these people developed suicidal thoughts and behavior as early as one week after they started taking the medication. There is a risk that you may experience changes in your mental health if you take an anticonvulsant medication such as pregabalin, but there may also be a risk that you will experience changes in your mental health if your condition is not treated. You and your doctor will decide whether the risks of taking an anticonvulsant medication are greater than the risks of not taking the medication. You, your family, or your caregiver should call your doctor right away if you experience any of the following symptoms: panic attacks; agitation or restlessness; new or worsening irritability, anxiety, or depression; acting on dangerous impulses; difficulty falling or staying asleep; aggressive, angry, or violent behavior; mania (frenzied, abnormally excited mood); talking or thinking about wanting to hurt yourself or end your life; withdrawing from friends and family; preoccupation with death and dying; giving away prized possessions; or any other unusual changes in behavior or mood. Be sure that your family or caregiver knows which symptoms may be serious so they can call the doctor if you are unable to seek treatment on your own.

What special dietary instructions should I follow?

Unless your doctor tells you otherwise, continue your normal diet.

What should I do if I forget a dose?

If you forget to take a dose and remember a few hours later, take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

What side effects can this medication cause?

Pregabalin may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • tiredness
  • dizziness
  • headache
  • dry mouth
  • nausea
  • vomiting
  • constipation
  • gas
  • bloating
  • ”high” or elevated mood
  • speech problems
  • difficulty concentrating or paying attention
  • confusion
  • difficulty remembering or forgetfulness
  • anxiety
  • lack of coordination
  • loss of balance or unsteadiness
  • uncontrollable shaking or jerking of a part of the body
  • muscle twitching
  • weakness
  • increased appetite
  • weight gain
  • swelling of the arms, hands, feet, ankles, or lower legs
  • back pain

Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately:

  • blurred vision, double vision, or other changes in eyesight
  • hives
  • rash
  • itching
  • blisters
  • swelling of the eyes face, throat, mouth, lips, gums, tongue, head or neck
  • shortness of breath
  • wheezing
  • muscle pain, tenderness, soreness, or weakness, especially if it comes along with fever
  • chest pain

If you have diabetes, you should know that pregabalin has caused skin sores in animals. Pay extra attention to your skin while taking pregabalin, and tell your doctor if you have any sores, redness, or skin problems.

Pregabalin may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting program online ( or by phone (1-800-332-1088).

What should I know about storage and disposal of this medication?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

In case of emergency/overdose

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

What other information should I know?

Keep all appointments with your doctor and the laboratory. Your doctor may order certain lab tests to check your body’s response to pregabalin.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

lyrica225mg pregabalin pregabalin25mg pregabalin100mg pregabalincapsule150mg

Brand names

  • Lyrica®

Lyrica will be designated a controlled substance, recommended for classification in the category with lowest potential for abuse or misuse relative to controlled substances in other categories.

LYRICA is a Schedule V controlled substance.
In a study of recreational users (N=15) of sedative/hypnotic drugs, including alcohol,Lyrica (450mg, single dose) received subjective ratings of “good drug effect,” “high” and “liking” to a degree that was similar to diazepam (30mg, single dose). In controlled clinical studies in over 5500 patients, 4 % of Lyrica-treated patients and 1 % of placebo treated patients overall reported euphoria as an adverse event, though in some patient populations studied, this reporting rate was higher and ranged from 1 to 12%.

In clinical studies, following abrupt or rapid discontinuation of pregabalin, some patients reported symptoms including insomnia, nausea, headache or diarrhea (see PRECAUTIONS, Abrupt Discontinuation), suggestive of physical dependence.

Anticonvulsants Market To 2016

Various anticonvulsants, both branded and off-label are being used for the treatment of many indications such as epilepsy, fibromyalgia, migraine, neuropathic pain, bipolar disorder and anxiety. The patents of leading anticonvulsants such as Topamax (topiramate), Trileptal (oxcarbazepine), Depakote (divalproex sodium), Keppra (levetiracetam), Lamictal (lamotrigine) and Tegretol (carbamazepine) expired in 2007-2008. The wide applicability of the anticonvulsants for management of the various indications has caused the emergence of generics for these anticonvulsants in the market. This generic erosion will cause decline in the anticonvulsant market in the future.

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Two anticonvulsants, Fosphenytoin and Stedesa have been filed in the US with FDA and 44% of the total anticonvulsants product pipeline is in Phase III clincal studies. The majority of these molecules are being studied as monotherapies for the treatment of epilepsy.The expected launch of these new anticonvusants in the future is expected to to stabilize the declining anticonvulsant market.

Lyrica (pregabalin) is the branded anriconvulsant product of Pfizer.Lyrica is indicated for the treatment of the epilepsy, fibromyalgia and neuropathic pain. Lyrica along with Neurontin (gabapentin) is the first line of therapy for the treatment of neuropathic pain, especially when tricyclic antidepressants are contraindicated. Lyrica is the only anticonvulsant which has been approved for the treatment of fibromyalgia. Lyrica generated revenue of $ 2.57 billion and $ 2.84 billion for Pfizer, in 2008 and 2009 respectively.

GBI Research, the leading business intelligence provider, has released its latest research, Anticonvulsants Market to 2016 – Cost Advantage and Dosage Convenience Provided by Generic Anticonvulsants Will Limit Commercial Opportunities for Novel Therapies, which provides insights into global anticonvulsant market and market forecast until 2016.

Report is built using data and information sourced from proprietary databases, primary and secondary research and in-house analysis by GBI Researchs team of industry experts.

The report provides an in-depth analysis of the top five therapeutic indications for which often anticonvulsants are prescribed which includes epilepsy, fibromyalgia, migraine, neuropathic pain and bipolar disorder. The report also examines the Global anticonvulsant treatment usage patterns for the covered indication. In addition, the report also includes insights into the anticonvulsant R&D pipeline.

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Many Folks Use The Anticonvulsant Valparin (Valproic Acid) To Manage Seizures

Brand title: Valparin Generic title: Valproic Acid Synonyms: Valprot, Convulex, Delepsine, Depakine, Deproic, Epilex, Epilim, Mylproin, Sprinkle, Valcote Description:

Valparin (Valproic Acid) is an anticonvulsant used to manage seizures. It may well be also used to deal with other ailments as determined by your medical professional.

What could be the most important details I really should know about Valparin?

* In uncommon instances, Valparin has brought on life-threatening liver failure, specifically in kids younger than 2 many years old. Young children of this age may well be at even increased threat for liver troubles if they use much more than a single seizure remedy, if they’ve a metabolic disorder, or if they’ve a brain condition creating mental impairment (such as Creutzfeldt-Jacob condition, Huntington condition, numerous sclerosis, or even a brain injury or infection).

* Valparin has also brought on uncommon instances of life-threatening pancreatitis (inflammation from the pancreas). Pancreatitis can come on suddenly and symptoms may well start even after you might have been taking Valparin for various many years.

* Look for unexpected emergency health interest when the individual taking this treatments has nausea, vomiting, abdomen pain, or loss of appetite, reduced fever, dark urine, clay-colored stools, or jaundice (yellowing from the epidermis or eyes). These symptoms may well be earlier indicators of liver harm. Some of these symptoms may well be also earlier indicators of pancreatitis.

* Do not use this remedy without having your doctor”s consent if you’re pregnant. It could cause harm towards unborn baby. Use an efficient form of birth manage, and tell your medical professional when you become pregnant throughout therapy.

* Do not stop taking the remedy even when you really feel much better. It is important to take Valparin often to stop seizures from recurring. Call your medical professional promptly if this treatments doesn’t appear for being working as well in stopping your seizures.

* Swallow the capsule whole. Do not crush, chew, or break a capsule mainly because the treatments may well irritate your mouth or throat once you swallow it.

* Carry an ID card or wear a health alert bracelet stating that you’re taking Valparin, in case of unexpected emergency. Any medical professional, dentist, or unexpected emergency health care provider who treats you really should realize that you’re taking Valparin.

* Stay clear of utilizing other drugs that make you sleepy (such as other seizure medicines, alcohol, cold treatments, pain remedy, muscle relaxers, and treatments for depression or anxiety). They can add to sleepiness brought on by Valparin.

What are the possible part results of Valparin?

Look for unexpected emergency health interest when the individual taking this treatments has nausea, vomiting, abdomen pain, or loss of appetite, reduced fever, dark urine, clay-colored stools, or jaundice (yellowing from the epidermis or eyes). These symptoms may well be earlier indicators of liver harm. Some of these symptoms may well be also earlier indicators of pancreatitis. Get unexpected emergency health assist if you might have any of these indicators of an allergic reaction: hives; trouble breathing; swelling of your face, lips, tongue, or throat.Call your medical professional at as soon as if you might have any of these serious part results:

* unexplained weakness with vomiting and confusion or fainting;

* simple bruising or bleeding, uncommon weakness;

* fever, epidermis rash, swollen glands;

* fever, chills, entire body aches, flu symptoms;

* urinating much less than usual;

* blood within your urine;

* hallucinations (seeing points that aren”t there);

* weakness, lack of coordination;

* a red, blistering, peeling epidermis rash;

* extreme drowsiness;

* uncommon bleeding or bruising; or

* double vision or back-and-forth movements from the eyes.Getting employed and prescribed the Anticonvulsant Valparin (Valproic Acid) to a lot of folks in a lot of years it functions excellent. In the event you require a lot more data on Generic Valparin see